Date
|
Topics
|
Slides/Lecture notes
|
Add'l resources
|
1/24
|
Introduction
Molecular biology primer
|
Lecture 1
Homework 1
|
|
1/29
|
Molecular biology primer
Perl/Perl Modules
|
Lecture 2
|
|
1/31
|
Perl/Perl Modules/BioPerl |
Lecture 3
|
|
2/5
|
Bioinformatics Databases |
Lecture 4
|
|
2/7
|
Bioinformatics Databases |
Lecture 5
Homework 2
|
|
2/12
|
Sequence alignment - exact matching
|
Lecture 6
|
|
2/14
|
Sequence alignment - suffix trees/suffix arrays SNOW DAY
|
|
|
2/19
|
Sequence alignment - inexact matching
|
Pevzner 6.4-6.10
Lecture 8
|
|
2/21
|
Sequence alignment - heuristics
|
Lecture 9
Project 1 handed out
|
BLOSUM62 matrix
Sample input file
Sample database
Sample parameters
Sample output
|
2/26
|
Multiple sequence alignments
|
Pevzner 6.10
Lecture 10
|
|
2/28
|
Construction of phylogenetic trees
|
Pevzner 10.5-10.12
Homework 3
Lecture 11
|
|
3/5
|
Tree analysis/Tree display
|
Lecture 12
|
|
3/7
|
Suffix trees
Suffix arrays
|
Pevzner 9.4-9.5
Lecture 13
|
Reminder: Daylight Savings Time ends on Sunday!
|
3/12
|
Genome sequence assembly
|
Pevzner 8.3-8.9
Lecture 14
|
|
3/14
|
Genome sequence assembly
|
no homework handed out
Lecture 15
|
|
3/19
|
Spring break
|
|
|
3/21
|
Spring break
|
|
|
3/26
|
Lessons from project 1
Dynamic programming recap
|
Project 1 due
Lecture 16
|
|
3/28
|
Gene finding
|
Pevzner chap. 11
Lecture 17
|
|
4/2 |
Midterm |
Passover - no homework handed out or due
|
|
4/4
|
Midterm recap/Gene finding
|
Project 2 suggestions
"Lecture" 18
|
|
4/9
|
Gene finding
|
Pevzner chap. 11
Project 2 handed out
Lecture 19
|
Project 1 evaluation criteria
smalltest-query.fa
smalltest-db.fa
bigtest-query.fa
bigtest-db.fa
swaptest.fa
BLOSUM80
fastaout.txt
|
4/11
|
Microarrays and data clustering
|
Pevzner chap. 10
Lecture 20
Homework 4
|
Project2 details
|
4/16
|
RNA structure prediction
|
Lecture 21
|
|
4/18
|
Open-source
|
Richard Stallman's talk @ 4 1115 CSIC
|
|
4/23
|
Protein structure prediction
|
Lecture 22
|
|
4/25
|
Protein structure prediction
Proteomics
|
Lecture 23
|
|
4/30
|
Mass Spectrometry
Gene Networks
|
Pevzner chap 8
Lecture 24
|
|
5/2
|
Real-life examples
|
Lecture 25
|
|
5/7
|
Recap/Review
|
Project 2 due!!
|
|
5/9
|
Recap/Review
Final thoughts
|
|
|
5/15 |
Final exam |
1:30-3:30pm CSIC 3120 |
|