Syllabus for CMSC423: Bioinformatic Algorithms, Databases, and Tools (Spring 2007)

Course information

Tentative syllabus 

 
Date
Topics
Slides/Lecture notes
Add'l resources
1/24
Introduction
Molecular biology primer
Lecture 1
Homework 1

1/29
Molecular biology primer
Perl/Perl  Modules
Lecture 2

1/31
Perl/Perl Modules/BioPerl Lecture 3

2/5
Bioinformatics Databases Lecture 4

2/7
Bioinformatics Databases Lecture 5
Homework 2

2/12
Sequence alignment - exact matching
Lecture 6

2/14
Sequence alignment - suffix trees/suffix arrays SNOW DAY


2/19
Sequence alignment - inexact matching
Pevzner 6.4-6.10
Lecture 8

2/21
Sequence alignment - heuristics
Lecture 9
Project 1 handed out
BLOSUM62 matrix
Sample input file
Sample database
Sample parameters
Sample output
2/26
Multiple sequence alignments
Pevzner 6.10
Lecture 10

2/28
Construction of phylogenetic trees
Pevzner 10.5-10.12
Homework 3
Lecture 11

3/5
Tree analysis/Tree display
Lecture 12

3/7
Suffix trees
Suffix arrays
Pevzner 9.4-9.5
Lecture 13
Reminder: Daylight Savings Time ends on Sunday!
3/12
Genome sequence assembly
Pevzner 8.3-8.9
Lecture 14

3/14
Genome sequence assembly
no homework handed out
Lecture 15

3/19
Spring break


3/21
Spring break


3/26
Lessons from project 1
Dynamic programming recap
Project 1 due
Lecture 16

3/28
Gene finding
Pevzner chap. 11
Lecture 17

4/2 Midterm
Passover - no homework handed out or due

4/4
Midterm recap/Gene finding
Project 2 suggestions
"Lecture" 18

4/9
Gene finding
Pevzner chap. 11
Project 2 handed out
Lecture 19
Project 1 evaluation criteria
smalltest-query.fa
smalltest-db.fa
bigtest-query.fa
bigtest-db.fa
swaptest.fa
BLOSUM80
fastaout.txt
4/11
Microarrays and data clustering
Pevzner chap. 10
Lecture 20
Homework 4
Project2 details
4/16
RNA structure prediction
Lecture 21

4/18
Open-source
Richard Stallman's talk @ 4 1115 CSIC

4/23
Protein structure prediction
Lecture 22

4/25
Protein structure prediction
Proteomics
Lecture 23

4/30
Mass Spectrometry
Gene Networks
Pevzner chap 8
Lecture 24

5/2
Real-life examples
Lecture 25

5/7
Recap/Review
Project 2 due!!

5/9
Recap/Review
Final thoughts



5/15 Final exam 1:30-3:30pm   CSIC 3120