| Citation |
BJ Haas, SL Salzberg, W Zhu, M Pertea, JE Allen, J Orvis, O White, CR Buell, JR Wortman
Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments.
Genome Biology, 9:R7 (2008) |
| Abstract |
ABSTRACT: EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation tool that reports eukaryotic gene structures as a weighted consensus of all available evidence. EVM, when combined with the Program to Assemble Spliced Alignments (PASA), yields a comprehensive, configurable annotation system that predicts protein-coding genes and alternatively spliced isoforms. Our experiments on both rice and human genome sequences demonstrate that EVM produces automated gene structure annotation approaching the quality of manual curation. |
| PubMed |
18190707
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| doi |
10.1186/gb-2008-9-1-r7
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| URL |
http://genomebiology.com/2008/9/1/R7
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