TY - JOUR T1 - InterPro in 2011: new developments in the family and domain prediction database. JF - Nucleic Acids Res Y1 - 2012 A1 - Hunter, Sarah A1 - Jones, Philip A1 - Mitchell, Alex A1 - Apweiler, Rolf A1 - Attwood, Teresa K A1 - Bateman, Alex A1 - Bernard, Thomas A1 - Binns, David A1 - Bork, Peer A1 - Burge, Sarah A1 - de Castro, Edouard A1 - Coggill, Penny A1 - Corbett, Matthew A1 - Das, Ujjwal A1 - Daugherty, Louise A1 - Duquenne, Lauranne A1 - Finn, Robert D A1 - Fraser, Matthew A1 - Gough, Julian A1 - Haft, Daniel A1 - Hulo, Nicolas A1 - Kahn, Daniel A1 - Kelly, Elizabeth A1 - Letunic, Ivica A1 - Lonsdale, David A1 - Lopez, Rodrigo A1 - Madera, Martin A1 - Maslen, John A1 - McAnulla, Craig A1 - McDowall, Jennifer A1 - McMenamin, Conor A1 - Mi, Huaiyu A1 - Mutowo-Muellenet, Prudence A1 - Mulder, Nicola A1 - Natale, Darren A1 - Orengo, Christine A1 - Pesseat, Sebastien A1 - Punta, Marco A1 - Quinn, Antony F A1 - Rivoire, Catherine A1 - Sangrador-Vegas, Amaia A1 - Selengut, Jeremy D A1 - Sigrist, Christian J A A1 - Scheremetjew, Maxim A1 - Tate, John A1 - Thimmajanarthanan, Manjulapramila A1 - Thomas, Paul D A1 - Wu, Cathy H A1 - Yeats, Corin A1 - Yong, Siew-Yit KW - Databases, Protein KW - Protein Structure, Tertiary KW - Proteins KW - Sequence Analysis, Protein KW - software KW - Terminology as Topic KW - User-Computer Interface AB -

InterPro (http://www.ebi.ac.uk/interpro/) is a database that integrates diverse information about protein families, domains and functional sites, and makes it freely available to the public via Web-based interfaces and services. Central to the database are diagnostic models, known as signatures, against which protein sequences can be searched to determine their potential function. InterPro has utility in the large-scale analysis of whole genomes and meta-genomes, as well as in characterizing individual protein sequences. Herein we give an overview of new developments in the database and its associated software since 2009, including updates to database content, curation processes and Web and programmatic interfaces.

VL - 40 CP - Database issue M3 - 10.1093/nar/gkr948 ER -