Center for Bioinformatics and Computational Biology

Liliana Florea

Liliana Photo Assistant Research Scientist
Center for Bioinformatics and Computational Biology
3119 Biomolecular Sciences Bldg. (#296)
University of Maryland
College Park, MD 20742
Ph: (301) 405-9901
E-mail: florea [at] umiacs.umd.edu

http://cbcb.umiacs.umd.edu/~florea/research/

Research

Genome analysis and comparison; cDNA-to-genome alignment; Gene and alternative splicing annotation; Microbial comparative genomics; MiRNA genomics; Computational vaccine design. [More]
 

Education

Ph.D., Computer Science and Engineering (2000) Penn State University
M.Sc., Computer Science and Engineering (1998) Penn State University
B.S., Computer Science (1994) University of Bucharest, Romania
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Selected publications

  1. Zhou, L., M. Pertea, A.L. Delcher, L. Florea (2009) Sim4cc: a cross-species spliced alignment program, Nucleic Acids Res. 37(11):e80. [Medline]
  2. Zimin, A.V., A.L. Delcher, L. Florea, D.R. Kelley, M.C. Schatz, D. Puiu, F. Hanrahan, G. Pertea, C.P. Van Tassell, T.S. Sonstegard, G. Marcais, M. Roberts, P. Subramanian, J.A. Yorke and S.L. Salzberg (2009) A whole-genome assembly of the domestic cow Bos taurus, Genome Biology 10(4):R42. [Medline]
  3. Zhou, L., J. Stanton, L. Florea (2008) Universal seeds for cDNA-to-genome comparison, BMC Bioinformatics, 9:36. [Medline]
  4. Zhou, L., L. Florea (2007) Designing sensitive and specific spaced seeds for cross-species mRNA-to-genome alignment, J. Comput. Biol. 14(2), 113-130. [Medline]
  5. Florea, L. (2006) Bioinformatics of alternative splicing and its regulation, Brief. Bioinform. 7(1), 55-69. [Medline]
  6. Florea, L., V. Di Francesco, J. Miller, R. Turner, C. Mobarry, A. Yao, M. Harris, B. Walenz, I. Dew, G. Merkulov, R. Charlab, Z. Deng, S. Istrail, P. Li, G. Sutton (2005) Gene and alternative splicing annotation with AIR, Genome Res. 15, 54-66. [Medline]
  7. Istrail, S., G.G. Sutton, L. Florea, A. Halpern, C.M. Mobarry, R. Lippert et al. (2004) Whole-genome shotgun assembly and comparison of human genome assemblies, Proc. Natl. Acad. Sci. USA 101(7), 1916-1921. [Medline]
  8. Lippert, R.A., X. Zhao, L. Florea, C. Mobarry, S. Istrail (2004) Finding anchors for genomic sequence comparison, Proc. 8th Intln. Conf. on Research in Computational Biology - RECOMB 2004, 233-241. [Abstract]
  9. Istrail, S., L. Florea, B.V. Halldorsson, O. Kohlbacher, R.S. Schwartz, V.B. Yap, J.W. Yewdell, S.L. Hoffman (2004) Comparative immunopeptidomics of humans and their pathogens, Proc. Natl. Acad. Sci. USA 101(36), 13268-13272. [Medline]
  10. Florea, L., M. McClelland, C. Riemer, S. Schwartz, W. Miller (2003) EnteriX 2003: Visualization tools for genome alignments of Enterobacteriaceae, Nucleic Acids Res. 31(13), 3527-3532. [Medline]
  11. McClelland, M., K.E. Sanderson, J. Spieth, S.W. Clifton, P. Latreille, L. Courtney, S. S. Porwollik, J. Ali, M. Dante, F. Du, S. Hou, D. Layman, S. Leonard, C Nguyen, K. Scott, A. Holmes, N. Grewal, E. Mulvaney, E. Ryan, H. Sun, L. Florea, W. Miller, T. Stoneking, M. Nhan, R. Waterston, R.K. Wilson (2001) Complete genome sequence of Salmonella enterica serovar Typhimurium LT2, Nature 413(6858), 852-856. [Medline]
  12. Venter J.C., M.D. Adams, G. Myers, P.W. Li, R. Mural, G.G. Sutton, ..., L. Florea, ..., X. Zhu (2001) The sequence of the human genome, Science 291(5507), 1304-1351. [Medline]
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