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Assembly and gene finding algorithms for genome
sequences generated by pyrosequencing
Funding:Uniformed
Services University of the Health Sciences, administered by the Henry
Jackson Foundation
Collaborators: Tim Read, Naval Medical Research Center
Lab members: Dan Sommer, Niranjan Nagarajan
This
project supports the development of software tools for the assembly
and annotation of genome sequence data generated using the sequencing
technology from 454 Life Sciences. These tools will be part of the
informatics infrastructure for the high-throughput sequencing of
bacterial pathogens and their near neighbors at the Biological
Defense Research Directorate of the Naval Medical Research Center, an
effort aimed at understanding pathogenicity and at providing a basis
for vaccine development
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New
technologies in diagnosis of enteric diseases
Funding: Bill and Melinda Gates Foundation
Collaborators: Colin Stine, University of Maryland School of Medicine
Lab members: James White
This
proposal is aimed at using genomic technologies to characterize
previously unknown bacterial causes for diarrhea in third world
countries.
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