@article {38190,
	title = {CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features},
	journal = {Genome BiologyGenome Biology},
	volume = {10},
	year = {2009},
	type = {10.1186/gb-2009-10-11-r131},
	abstract = {CTCF (CCCTC-binding factor) is an evolutionarily conserved zinc finger protein involved in diverse functions ranging from negative regulation of MYC, to chromatin insulation of the beta-globin gene cluster, to imprinting of the Igf2 locus. The 11 zinc fingers of CTCF are known to differentially contribute to the CTCF-DNA interaction at different binding sites. It is possible that the differences in CTCF-DNA conformation at different binding sites underlie CTCF{\textquoteright}s functional diversity. If so, the CTCF binding sites may belong to distinct classes, each compatible with a specific functional role.},
	isbn = {1465-6906},
	author = {Essien, Kobby and Vigneau, Sebastien and Apreleva, Sofia and Singh, Larry N. and Bartolomei, Marisa S. and Sridhar Hannenhalli}
}
