Date 
       | 
      Topics 
       | 
      Slides/Lecture notes 
       | 
      Add'l resources 
       | 
    
    
      1/24 
       | 
      Introduction 
Molecular biology primer 
       | 
      Lecture 1 
      Homework 1 
       | 
       
       | 
    
    
      1/29 
       | 
      Molecular biology primer 
Perl/Perl  Modules 
       | 
      Lecture 2 
       | 
       
       | 
    
    
      1/31 
       | 
      Perl/Perl Modules/BioPerl | 
      Lecture 3 
       | 
       
       | 
    
    
      2/5 
       | 
      Bioinformatics Databases | 
      Lecture 4 
       | 
       
       | 
    
    
      2/7 
       | 
      Bioinformatics Databases | 
      Lecture 5 
      Homework 2 
       | 
       
       | 
    
    
      2/12 
       | 
      Sequence alignment - exact matching 
       | 
      Lecture 6 
       | 
       
       | 
    
    
      2/14 
       | 
      Sequence alignment - suffix trees/suffix arrays SNOW DAY 
       | 
       
       | 
       
       | 
    
    
      2/19 
       | 
      Sequence alignment - inexact matching 
       | 
      Pevzner 6.4-6.10 
      Lecture 8 
       | 
       
       | 
    
    
      2/21 
       | 
      Sequence alignment - heuristics 
       | 
      Lecture 9 
      Project 1 handed out 
       | 
      BLOSUM62 matrix 
      Sample input file 
      Sample database 
      Sample parameters 
      Sample output 
       | 
    
    
      2/26 
       | 
      Multiple sequence alignments 
       | 
      Pevzner 6.10 
      Lecture 10 
       | 
       
       | 
    
    
      2/28 
       | 
      Construction of phylogenetic trees 
       | 
      Pevzner 10.5-10.12 
      Homework 3 
      Lecture 11 
       | 
       
       | 
    
    
      3/5 
       | 
      Tree analysis/Tree display 
       | 
      Lecture 12 
       | 
       
       | 
    
    
      3/7 
       | 
      Suffix trees 
Suffix arrays 
       | 
      Pevzner 9.4-9.5 
      Lecture 13 
       | 
      Reminder: Daylight Savings Time ends on Sunday! 
       | 
    
    
      3/12 
       | 
      Genome sequence assembly 
       | 
      Pevzner 8.3-8.9 
      Lecture 14 
       | 
       
       | 
    
    
      3/14 
       | 
      Genome sequence assembly 
       | 
      no homework handed out 
      
Lecture 15 
       | 
       
       | 
    
    
      3/19 
       | 
      Spring break 
       | 
       
       | 
       
       | 
    
    
      3/21 
       | 
      Spring break 
       | 
       
       | 
       
       | 
    
    
      3/26 
       | 
      Lessons from project 1 
Dynamic programming recap 
       | 
      Project 1 due 
      Lecture 16 
       | 
       
       | 
    
    
      3/28 
       | 
      Gene finding 
       | 
      Pevzner chap. 11 
      Lecture 17 
       | 
       
       | 
    
    
      | 
      4/2 | 
      Midterm | 
       
      Passover - no homework handed out or due 
       | 
       
       | 
    
    
      4/4 
       | 
      Midterm recap/Gene finding 
       | 
      Project 2 suggestions 
      "Lecture" 18 
       | 
       
       | 
    
    
      4/9 
       | 
      Gene finding 
       | 
      Pevzner chap. 11 
      
Project 2 handed out 
      Lecture 19 
       | 
      Project 1 evaluation criteria 
      smalltest-query.fa 
      smalltest-db.fa 
      bigtest-query.fa 
      bigtest-db.fa 
      swaptest.fa 
      BLOSUM80 
      fastaout.txt 
       | 
    
    
      4/11 
       | 
      Microarrays and data clustering 
       | 
      Pevzner chap. 10 
      Lecture 20 
      Homework 4 
       | 
      Project2 details 
       | 
    
    
      4/16 
       | 
      RNA structure prediction 
       | 
      Lecture 21 
       | 
       
       | 
    
    
      4/18 
       | 
      Open-source 
       | 
      Richard Stallman's talk @ 4 1115 CSIC 
       | 
       
       | 
    
    
      4/23 
       | 
      Protein structure prediction 
       | 
      Lecture 22 
       | 
       
       | 
    
    
      4/25 
       | 
      Protein structure prediction 
Proteomics 
       | 
      Lecture 23 
       | 
       
       | 
    
    
      4/30 
       | 
      Mass Spectrometry 
Gene Networks 
       | 
      Pevzner chap 8 
      Lecture 24 
       | 
       
       | 
    
    
      5/2 
       | 
      Real-life examples 
       | 
      Lecture 25 
       | 
       
       | 
    
    
      5/7 
       | 
      Recap/Review 
       | 
      Project 2 due!! 
       | 
       
       | 
    
    
      5/9 
       | 
      Recap/Review 
Final thoughts 
       | 
       
       | 
       
       | 
    
    
      | 5/15 | 
      Final exam | 
      1:30-3:30pm   CSIC 3120 | 
       |