Computational biologists at the University of Maryland are partnering with ophthalmologists from the renowned Wilmer Eye Institute at Johns Hopkins University to improve therapeutic options for people suffering from chronic ocular diseases.
Jason Fan’s current goal is to design small data-structures—or indexes—to support fast sequence queries against tens of human scale genomes, or tens of thousands of bacterial genomes.
He will use the funding from the Chan Zuckerberg Initiative to improve upon a “constellation” of inter-related tools his lab has developed to process genomic data.
Professor Michael Cummings and others will analyze the synthetic process that goes into manufacturing antisense oligonucleotides—small pieces of DNA or RNA that can bind to specific molecules of RNA.